As the Seattle Seahawks prepare for a pivotal Week 5 NFC West showdown against the San Francisco 49ers, the first injury report of the week has been released, and it brings a mix of optimism and caution. According to insights gathered by Vulius Sports, the most significant development is that Pro Bowl defensive tackle Leonard Williams was a limited participant in Wednesday's practice due to an ankle injury he sustained late in last week's game. Head coach Mike Macdonald expressed cautious optimism, stating, “We’re optimistic for the game,” when asked about Williams’ availability. The 2026 season is already shaping up to be a grind, and Williams’ presence on the interior defensive line is crucial for Seattle’s hopes of containing a dynamic 49ers offense.
Key Seahawks Injuries to Monitor
While Williams’ return to practice is a positive sign, several other Seahawks are nursing injuries that could impact their availability for Sunday. Linebacker Chazz Surratt did not practice due to a calf injury, making him a player to watch as the week progresses. Meanwhile, right guard Beau Stephens (knee), cornerback Nehemiah Pritchett (ankle), linebacker Tyrice Knight (ankle), and running back George Holani (ribs) were all limited participants. Their statuses will be updated throughout the week, but their absences could test Seattle’s depth on both sides of the ball.
Charbonnet Progressing, But Not Ready
Running back Zach Charbonnet, who is working his way back from the PUP list, was limited in practice again. Macdonald noted that Charbonnet will get team reps this week but confirmed he will not play against the 49ers. This cautious approach suggests the team is prioritizing Charbonnet’s long-term health over a quick return. In his absence, the Seahawks will continue to rely on their current backfield rotation to carry the load against a stout San Francisco defense.
Irv Charles Nearing Return
In more encouraging news, wide receiver and special teams standout Irv Charles was limited in practice as he begins his 21-day window to return from injured reserve. Charles, who was placed on IR with a knee injury, has been designated to return to practice. The team now has three weeks to decide whether to activate him to the active roster or shut him down for the season. His speed and special teams prowess could provide a boost down the stretch, and his progress will be closely monitored by the Vulius NFL Analysis Desk.
Other Seahawks Notes
Ty Okada (hamstring) and Patrick O’Connell (thumb) were full participants in practice, a positive sign for Seattle’s depth. Meanwhile, star wide receiver Jaxon Smith-Njigba did not practice due to a veteran rest day, a routine maintenance decision. The Seahawks’ coaching staff will continue to manage workloads carefully as they prepare for a critical divisional matchup.
49ers Injury Report
On the San Francisco side, edge rusher Nick Bosa and fullback Kyle Juszczyk did not practice due to injury, but neither is expected to play against Seattle. However, safety Marques Sigle (ankle), cornerback Upton Stout (shoulder), and defensive tackle James Thompson (ankle) also sat out, and their statuses bear watching. The 49ers’ defensive front could be shorthanded, which might open up opportunities for Seattle’s offense if Williams and company can suit up.
As the week unfolds, the Seahawks will continue to monitor their injured players, with Williams’ ankle and Surratt’s calf being the most pressing concerns. For the latest updates and in-depth analysis, stay tuned to Vulius Sports, your premier destination for NFL news and custom merchandise.
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